If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Job Role: We are looking for dynamic, creative, and talented computational chemist to join our expanding Discovery & Medicinal Chemistry Department. Reporting to the Director of Medicinal Chemistry, you will apply your expertise, leadership and guidance to discover and develop novel small-molecule therapeutic agents. You will be working within a patient-focused, science-driven, and multi-disciplinary biopharmaceutical environment, covering all stages of the drug discovery process. You will collaborate with scientists from other disciplines within Jazz Pharmaceuticals and with external collaborators to build an innovative portfolio of therapeutics across our exciting and growing oncology and neuroscience pipelines. Working at the forefront of drug discovery you will advance projects from target selection to preclinical drug candidates and FiH trials, and contribute to the growth of the medicinal chemistry team. Key Responsibilities: Utilize modern molecular modelling methods to support different stages of R&D programs. Collaborate effectively with other departments and functions to advance research discovery projects expeditiously from hit identification to high quality preclinical candidates. Design, lead and drive computational studies on projects throughout the several discovery phases and ensure execution on agreed deliverables. Opportunities to lead or co-lead projects in addition to drive discipline-specific endeavours. Set the vision and strategy for computational chemistry. Foster innovative thinking in all areas of departmental activities, with a particular focus on computational and medicinal chemistry. Manage CRO compchem activities, providing expertise and guidance. Present plans and results internally, including at board level, and externally at conferences. Contribute to the writing of patent applications, scientific publications, and internal reports. Develop and mentor less experienced staff. Keep up to date with the latest scientific advances and trends in drug discovery to deliver the next-generation therapies. Undertake ongoing professional development by attending relevant training and conferences. Requirements & Qualifications: MSc/PhD in a relevant scientific discipline (Pharmaceutical Sciences, Chemistry, Computational Chemistry) with a solid foundation in molecular modelling built in a pharma/biotech/CRO setting. Expert knowledge in CADD software packages and modern molecular modelling techniques. Sound knowledge in cutting-edge cheminformatic tools, AI/ML-enabled technologies, and in silico drug design, including both structure- and ligand-based methodologies. Passion for drug discovery with a deep entrepreneurial and problem-solving attitude. Mastery of all the theoretical and practical principles of medicinal chemistry and drug design. Broad knowledge of biophysical, biochemical, and cell-based assays used in the early stages of the drug discovery process. In depth understanding of multi-parameter optimization and ability to integrate disease biology, ADME/DMPK and toxicology data to solve complex drug discovery problems. Excellent leadership, management, organizational and team-working skills, and a talent to deliver project milestones within the expected time frame. Demonstrated track record of scientific publications. Exceptional oral, written, and interpersonal communication skills, and ability to develop and grow strong cross-functional collaborations. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
Sep 04, 2025
Full time
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Job Role: We are looking for dynamic, creative, and talented computational chemist to join our expanding Discovery & Medicinal Chemistry Department. Reporting to the Director of Medicinal Chemistry, you will apply your expertise, leadership and guidance to discover and develop novel small-molecule therapeutic agents. You will be working within a patient-focused, science-driven, and multi-disciplinary biopharmaceutical environment, covering all stages of the drug discovery process. You will collaborate with scientists from other disciplines within Jazz Pharmaceuticals and with external collaborators to build an innovative portfolio of therapeutics across our exciting and growing oncology and neuroscience pipelines. Working at the forefront of drug discovery you will advance projects from target selection to preclinical drug candidates and FiH trials, and contribute to the growth of the medicinal chemistry team. Key Responsibilities: Utilize modern molecular modelling methods to support different stages of R&D programs. Collaborate effectively with other departments and functions to advance research discovery projects expeditiously from hit identification to high quality preclinical candidates. Design, lead and drive computational studies on projects throughout the several discovery phases and ensure execution on agreed deliverables. Opportunities to lead or co-lead projects in addition to drive discipline-specific endeavours. Set the vision and strategy for computational chemistry. Foster innovative thinking in all areas of departmental activities, with a particular focus on computational and medicinal chemistry. Manage CRO compchem activities, providing expertise and guidance. Present plans and results internally, including at board level, and externally at conferences. Contribute to the writing of patent applications, scientific publications, and internal reports. Develop and mentor less experienced staff. Keep up to date with the latest scientific advances and trends in drug discovery to deliver the next-generation therapies. Undertake ongoing professional development by attending relevant training and conferences. Requirements & Qualifications: MSc/PhD in a relevant scientific discipline (Pharmaceutical Sciences, Chemistry, Computational Chemistry) with a solid foundation in molecular modelling built in a pharma/biotech/CRO setting. Expert knowledge in CADD software packages and modern molecular modelling techniques. Sound knowledge in cutting-edge cheminformatic tools, AI/ML-enabled technologies, and in silico drug design, including both structure- and ligand-based methodologies. Passion for drug discovery with a deep entrepreneurial and problem-solving attitude. Mastery of all the theoretical and practical principles of medicinal chemistry and drug design. Broad knowledge of biophysical, biochemical, and cell-based assays used in the early stages of the drug discovery process. In depth understanding of multi-parameter optimization and ability to integrate disease biology, ADME/DMPK and toxicology data to solve complex drug discovery problems. Excellent leadership, management, organizational and team-working skills, and a talent to deliver project milestones within the expected time frame. Demonstrated track record of scientific publications. Exceptional oral, written, and interpersonal communication skills, and ability to develop and grow strong cross-functional collaborations. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Brief Description: The Principal, AI Data Scientist will be responsible for supporting the implementation of innovative, complex and transformative AI/ML/GenAI solutions across the areas of Clinical Trial Execution and Digital Healthcare across Jazz Research and Development. Essential Functions Support the development and implementation of AI/ML/GenAI solutions to optimize clinical trial operations, including such areas as patient recruitment, patient retention, real-time data monitoring and automated data collection system build. Support the development and implementation GenAI applications for automated clinical trial documentation generation including such areas medical reports, clinical study reports, protocols and patient narratives. Support the development and implementation of Digital Healthcare applications for medical and scientific tools, RWE new ways of generating real data, patients' engagement. Support the design and develop predictive models and generative AI solutions using diverse healthcare data sources, including clinical trials data, electronic health records, wearable devices, patient-reported outcomes, HEOR data, phase IV studies. Collaborate with cross-functional teams including clinical operations, clinical development, data science and global medical & scientific affairs, RWE and patients working groups to tackle business challenges and bring value of AI-driven solutions. Ensuring compliance with regulatory requirements and data privacy standards. Facilitate knowledge sharing and exchange within Jazz Data Science and across Jazz Research and Development. Required Knowledge, Skills and Abilities Strong programming skills in Python, R, or similar languages, with experience in modern ML frameworks (PyTorch, TensorFlow). Demonstrated experience with generative AI technologies, including LLM architectures and frameworks. Knowledge/experience with digital healthcare tools design and development Experience with natural language processing and generative AI for medical text analysis, generation, and interpretation. Demonstrated ability to build relationships with stakeholders and subject matter experts. Familiarity with high compute cloud-based platforms and services, in particular AWS. Familiarity with code version control and MLOps deployment approaches. Ability to understand healthcare challenges and adapt accordingly the AI solutions. Cross-functions high adaptability to meet cross organization goals. Required/Preferred Education Advanced degree (MS or PhD) in Data Science, Computer Science, Biostatistics, or related field 3 - 5 years of related professional experience, with 1+ years of experience applying AI/ML techniques to healthcare or clinical research data. Experience in healthcare/AI implementation in healthcare field is a plus. Knowledge in digital healthcare tools design and development Description of Physical Demands Occasional mobility within office environment Routinely sitting for extended periods of time Constantly operating a computer, printer, telephone and other similar office machinery Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
Sep 04, 2025
Full time
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. Brief Description: The Principal, AI Data Scientist will be responsible for supporting the implementation of innovative, complex and transformative AI/ML/GenAI solutions across the areas of Clinical Trial Execution and Digital Healthcare across Jazz Research and Development. Essential Functions Support the development and implementation of AI/ML/GenAI solutions to optimize clinical trial operations, including such areas as patient recruitment, patient retention, real-time data monitoring and automated data collection system build. Support the development and implementation GenAI applications for automated clinical trial documentation generation including such areas medical reports, clinical study reports, protocols and patient narratives. Support the development and implementation of Digital Healthcare applications for medical and scientific tools, RWE new ways of generating real data, patients' engagement. Support the design and develop predictive models and generative AI solutions using diverse healthcare data sources, including clinical trials data, electronic health records, wearable devices, patient-reported outcomes, HEOR data, phase IV studies. Collaborate with cross-functional teams including clinical operations, clinical development, data science and global medical & scientific affairs, RWE and patients working groups to tackle business challenges and bring value of AI-driven solutions. Ensuring compliance with regulatory requirements and data privacy standards. Facilitate knowledge sharing and exchange within Jazz Data Science and across Jazz Research and Development. Required Knowledge, Skills and Abilities Strong programming skills in Python, R, or similar languages, with experience in modern ML frameworks (PyTorch, TensorFlow). Demonstrated experience with generative AI technologies, including LLM architectures and frameworks. Knowledge/experience with digital healthcare tools design and development Experience with natural language processing and generative AI for medical text analysis, generation, and interpretation. Demonstrated ability to build relationships with stakeholders and subject matter experts. Familiarity with high compute cloud-based platforms and services, in particular AWS. Familiarity with code version control and MLOps deployment approaches. Ability to understand healthcare challenges and adapt accordingly the AI solutions. Cross-functions high adaptability to meet cross organization goals. Required/Preferred Education Advanced degree (MS or PhD) in Data Science, Computer Science, Biostatistics, or related field 3 - 5 years of related professional experience, with 1+ years of experience applying AI/ML techniques to healthcare or clinical research data. Experience in healthcare/AI implementation in healthcare field is a plus. Knowledge in digital healthcare tools design and development Description of Physical Demands Occasional mobility within office environment Routinely sitting for extended periods of time Constantly operating a computer, printer, telephone and other similar office machinery Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. The Senior Principal will be responsible for leading projects related to data engineering requirements and initiatives across Jazz Research and Development. The Senior Principal will lead data projects from across the business including Clinical, Pre-Clinical, Non-Clinical, Chemistry, RWD and Omics. Essential Functions Lead the design, development and maintenance of data pipelines for processing Research and Development data from diverse sources (Clinical Trials, Medical Devices, Pre-Clinical, Omics, Real World Data) utilizing the AWS technology platform. Create and optimize ETL/ELT processes for structured and unstructured data using Python, R, SQL, AWS services and other tools. Build and maintain data repositories using AWS S3 and FSx technologies. Establish data warehousing solutions using Amazon Redshift. Build and maintain standard data models. Own data quality frameworks, validation processes and KPIs to ensure accuracy and consistency of data pipelines. Implement data versioning and lineage tracking to support data traceability, regulatory compliance and audit requirements. Create and maintain documentation for data processes, architectures, and workflows. Implement modern software development best practices (e.g. Code Versioning, DevOps, CD/CI). Support collaboration with RnD Researchers, Data scientists and Stakeholders to understand data requirements and deliver appropriate solutions in a global working model. Maintain compliance with data privacy regulations such as HIPAA, GDPR May be required to develop, deliver or support data literacy training across R&D. Required Knowledge, Skills and Abilities Expert knowledge of data engineering tools such as Python, R and SQL for data processing. Expert proficiency with AWS services particularly S3, Redshift, FSx, Glue, Lambda. Expert proficiency with relational databases. Strong background in data modeling and database design. Strong knowledge with unstructured database technologies (e.g. NoSQL) and other database types (e.g. Graph). Experience with Containerization such as Docker and EKS/Kubernetes. Experience with one or more RnD research process and associated regulatory requirements. Exposure to healthcare data standards (CDISC, HL7, FHIR, SNOMED CT, OMOP, DICOM). Experience to big data technologies and handling. Knowledge of machine learning operations (MLOps) and model deployment. Strong problem-solving and analytical abilities. Excellent communication skills for collaborating with stakeholders. Experience working in an Agile development environment. Required/Preferred Education Bachelor's Degree in Computer Science, Statistics, Mathematics, Life Sciences, or other relevant scientific fields; Master's Degree preferred 5-7 years of experience in data engineering, with at least 2 years focusing on healthcare, research or clinical related data Description of Physical Demands Occasional mobility within office environment Routinely sitting for extended periods of time Constantly operating a computer, printer, telephone and other similar office machinery Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
Sep 04, 2025
Full time
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information. The Senior Principal will be responsible for leading projects related to data engineering requirements and initiatives across Jazz Research and Development. The Senior Principal will lead data projects from across the business including Clinical, Pre-Clinical, Non-Clinical, Chemistry, RWD and Omics. Essential Functions Lead the design, development and maintenance of data pipelines for processing Research and Development data from diverse sources (Clinical Trials, Medical Devices, Pre-Clinical, Omics, Real World Data) utilizing the AWS technology platform. Create and optimize ETL/ELT processes for structured and unstructured data using Python, R, SQL, AWS services and other tools. Build and maintain data repositories using AWS S3 and FSx technologies. Establish data warehousing solutions using Amazon Redshift. Build and maintain standard data models. Own data quality frameworks, validation processes and KPIs to ensure accuracy and consistency of data pipelines. Implement data versioning and lineage tracking to support data traceability, regulatory compliance and audit requirements. Create and maintain documentation for data processes, architectures, and workflows. Implement modern software development best practices (e.g. Code Versioning, DevOps, CD/CI). Support collaboration with RnD Researchers, Data scientists and Stakeholders to understand data requirements and deliver appropriate solutions in a global working model. Maintain compliance with data privacy regulations such as HIPAA, GDPR May be required to develop, deliver or support data literacy training across R&D. Required Knowledge, Skills and Abilities Expert knowledge of data engineering tools such as Python, R and SQL for data processing. Expert proficiency with AWS services particularly S3, Redshift, FSx, Glue, Lambda. Expert proficiency with relational databases. Strong background in data modeling and database design. Strong knowledge with unstructured database technologies (e.g. NoSQL) and other database types (e.g. Graph). Experience with Containerization such as Docker and EKS/Kubernetes. Experience with one or more RnD research process and associated regulatory requirements. Exposure to healthcare data standards (CDISC, HL7, FHIR, SNOMED CT, OMOP, DICOM). Experience to big data technologies and handling. Knowledge of machine learning operations (MLOps) and model deployment. Strong problem-solving and analytical abilities. Excellent communication skills for collaborating with stakeholders. Experience working in an Agile development environment. Required/Preferred Education Bachelor's Degree in Computer Science, Statistics, Mathematics, Life Sciences, or other relevant scientific fields; Master's Degree preferred 5-7 years of experience in data engineering, with at least 2 years focusing on healthcare, research or clinical related data Description of Physical Demands Occasional mobility within office environment Routinely sitting for extended periods of time Constantly operating a computer, printer, telephone and other similar office machinery Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .
We re delighted to be recruiting a Prospect Research Manager for a brilliant health charity with ambitious plans to grow philanthropic income through major fundraising campaigns. This is a fantastic opportunity to play a central role in unlocking new funding opportunities, providing high-quality research and insight that will shape donor engagement and help secure transformational support. You ll be part of a high-performing development team working at the forefront of medical research, supporting scientists and clinicians making life-changing discoveries. Alongside a generous benefits package, you ll gain exposure to high-value fundraising at principal gift level, and the opportunity to mentor and develop a junior team member. Key Responsibilities: Devise and implement targeted prospecting strategies to identify and qualify high-net-worth individuals and corporates. Deliver insightful prospect briefings and research to inform cultivation and engagement strategies. Conduct due diligence and reputational risk assessments, ensuring compliance with data protection. Support fundraisers through prospect management, portfolio development and network mapping. Line manage and develop a Prospect Research Executive. About You: Established experience in prospect research within charity or higher education sector, with a proven track record in identifying, assessing and qualifying major donor and/or corporate prospects. Strong knowledge of research tools, data protection, and wealth/capacity ratings. Skilled communicator, able to present complex insights clearly and persuasively. Experience with CRM systems (ideally Raiser s Edge NXT). How to Apply To apply, please submit your CV demonstrating your suitability for this role by clicking the 'apply now' button (please do not apply via email). We aim to get back to all successful candidates within 48 working hours. Commitment to Diversity The Talent Set are committed to diverse and inclusive recruitment practices, ensuring equal opportunities for all applicants regardless of race, sexual orientation, disability, age, or gender. We actively encourage applications from a wide range of backgrounds and are always happy to make reasonable adjustments to ensure a fair recruitment process.
Aug 29, 2025
Full time
We re delighted to be recruiting a Prospect Research Manager for a brilliant health charity with ambitious plans to grow philanthropic income through major fundraising campaigns. This is a fantastic opportunity to play a central role in unlocking new funding opportunities, providing high-quality research and insight that will shape donor engagement and help secure transformational support. You ll be part of a high-performing development team working at the forefront of medical research, supporting scientists and clinicians making life-changing discoveries. Alongside a generous benefits package, you ll gain exposure to high-value fundraising at principal gift level, and the opportunity to mentor and develop a junior team member. Key Responsibilities: Devise and implement targeted prospecting strategies to identify and qualify high-net-worth individuals and corporates. Deliver insightful prospect briefings and research to inform cultivation and engagement strategies. Conduct due diligence and reputational risk assessments, ensuring compliance with data protection. Support fundraisers through prospect management, portfolio development and network mapping. Line manage and develop a Prospect Research Executive. About You: Established experience in prospect research within charity or higher education sector, with a proven track record in identifying, assessing and qualifying major donor and/or corporate prospects. Strong knowledge of research tools, data protection, and wealth/capacity ratings. Skilled communicator, able to present complex insights clearly and persuasively. Experience with CRM systems (ideally Raiser s Edge NXT). How to Apply To apply, please submit your CV demonstrating your suitability for this role by clicking the 'apply now' button (please do not apply via email). We aim to get back to all successful candidates within 48 working hours. Commitment to Diversity The Talent Set are committed to diverse and inclusive recruitment practices, ensuring equal opportunities for all applicants regardless of race, sexual orientation, disability, age, or gender. We actively encourage applications from a wide range of backgrounds and are always happy to make reasonable adjustments to ensure a fair recruitment process.
